What Are Antioxidants?
- Cynthia A. Barrington, BCHHP, CNHP

- May 30
- 2 min read
Updated: Jun 14
Antioxidants are compounds that protect the body from free radicals. Free radicals are unstable atoms that cause cellular damage known as oxidative stress. Oxidative stress is the underlying cause of many chronic health problems like aging, cardiovascular disease, anemia, and cancer.

Vitamin C and vitamin E are among the most important vitamins and are potent natural antioxidants. Natural antioxidants are mostly found in plant sources. Fruits and vegetables that are red, orange, and blue have the highest antioxidant activity. Other natural antioxidants are beta-carotene, lycopene, selenium, and flavonoids
Antioxidants increase shelf life of foods (and people!). Manufactures add antioxidants, like vitamin C (ascorbic acid, usually synthetic), as food additives.
Drugs that Deplete Antioxidants
Avoid these like your life depends on because it does.
Doxorubicin (antineoplastic)
Azidothymidine (antiretroviral)
Cisplatin (antineoplastic)
Diclofenac (anti-inflammatory)
Paracetamol (analgesia)
Chlorpromazine (antipsychotic)
Benefits of Antioxidants
Anti-aging (limits the process of growing old)
Anticancer (inhibits growth of cancer)
Anti-Inflammatory (controls inflammation)
Antioxidant (protects against oxidation)
Protects against many types of diseases
Protects eye health
Protects brain function
Improves mental health
Keeps skin healthy
Improves gut health
Symptoms of Antioxidant Deficiency
Cancer
Cardiovascular disease
Congestive heart failure
COPD
Eye disease, including cataracts
Hypertension
Increased oxidative stress
Inflammation
Neurological disease, like Alzheimer's
Parkinson's disease
Renal disease
Rheumatoid arthritis
Causes of Antioxidant Deficiency
Air pollution
Asbestos
Bacterial infections
Cigarette smoke
Fungal infections
High blood sugar levels
Intense or prolonged exercise
Too much or too little oxygen in the body
Toxins
Viral infections
Natural Sources of Antioxidants
Blueberries
Broccoli flowers
Chocolate
Coffee
Fish
Grapes
Green tea
Lemons
Meat
Oranges
Plums
Prunes
Red beans
Strawberries
Tomato
Did you know lycopene, found in tomatoes, is very protective against prostate cancer?
Resources
1) Zehiroglu, C., & Sarikaya, S. B. O. (2019). The importance of antioxidants and place in today’s scientific and technological studies. Journal of Food Science and Technology, 56(11), 4757–4774. https://doi.org/10.1007/s13197-019-03952-x
2) BSc, A. A., PhD. (2023, July 12). Antioxidants explained in simple terms. Healthline. https://www.healthline.com/nutrition/antioxidants-explained#free-radicals
3) Janciauskiene, S. (2020). The beneficial effects of antioxidants in health and diseases. Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation, 7(3), 182–202. https://doi.org/10.15326/jcopdf.7.3.2019.0152
4) Pham-Huy, L. A., He, H., & Pham-Huy, C. (2008, June 1). Free radicals, antioxidants in disease and health. https://pmc.ncbi.nlm.nih.gov/articles/PMC3614697/#sec5
5) Deavall, D. G., Martin, E. A., Horner, J. M., & Roberts, R. (2012). Drug-Induced Oxidative stress and toxicity. Journal of Toxicology, 2012, 1–13. https://doi.org/10.1155/2012/645460
6) Kahn, J. (2022, August 26). Nine benefits of antioxidants: From disease prevention to healthy aging. Live Science. https://www.livescience.com/benefits-of-antioxidants




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